Doctors, scientists and politicians alike have all been talking about vaccines, as the world today struggles to contain the coronavirus pandemic. Yet only the gullible would assume that vaccine production is anything but a lengthy, laborious process that often falls short. Let's take Dengue for example, a mosquito-borne disease that has assailed the tropics for centuries and is forcing South-East Asia & Latin America today to face two epidemics. In 2015, the first Dengue vaccine was registered but it was found to increase disease severity in dengue-naive individuals (i.e those who had never been infected before). The following study investigates TAK-003, a promising vaccine that may (or may not) pave the way to Dengue immunity for all, naive and otherwise.